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4.1.4.2 Intraperitoneal injection Used, especially in models of male infertility, to evaluate systemic effects on oxidative or hormonal markers

Key Preclinical Study (Neelakantan et al., 2018): Treatment in diet-induced obese mice produced progressive body weight loss, reduced white adipose tissue mass and adipocyte size, decreased total cholesterol, and no changes in food intake effects were metabolic, not appetite-driven

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Rapisarda LM (1957) Experimental research on liver damage induced by anesthetics & under the protective effect of thioctic acid

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